简介
2005.09-2009.06: 华中科技大学, 生物技术, 学士
2010.09-2017.03: 华中科技大学, 生物医学工程, 博士
2017.03 -2021.3: 华中科技大学, RNA 聚合酶筛选与RNA体外制备, 博士后
2021.03 -至 今: 中山大学附属第七医院, mRNA药物设计和开发, 特评助理研究员
发表论文/著作
(1) Yuandong Xu#; Yuexiao Hu#; Heng Xia H.#; Shiqiang Zhang; Hanqi Lei; Ze Xiu Xiao; Jinjin Chen; Jun Pang*; Gao-Feng Zha* ; Delivery of mRNA Vaccine with 1, 2-Diesters-Derived Lipids Elicits Fast Liver Clearance for Safe and Effective Cancer Immunotherapy, Advanced Healthcare Materials, 2024, 13(5)
(2) Xia H.#; He Y. R#; Zhan X. Y*; Zha G. F.* ; Mpox virus mRNA-lipid nanoparticle vaccine candidates evoke antibody responses and drive protection against the Vaccinia virus challenge in mice, Antiviral Res, 2023,
216: 0-105668.
(3) Xia, H.#; Yu, B#; Jiang, Y; Cheng, R; Lu, X; Wu, H; Zhu, B* ; Psychrophilic phage VSW-3 RNA polymerase reduces both terminal and full-length dsRNA byproducts in in vitro transcription, RNA Biol, 2022, 19(1): 1130-1142
(4) Wang, Guoquan; Cheng, Rui; Chen, Qiubing;Hao*,Xia, Heng*; mRNA produced by VSW-3 RNAP has high-level translation efficiency with low inflammatory stimulation, Cell Insight,2022,100056.
(5) Xia, H.#, Chen, D. , Wu, Q. , Wu, G. , & Zhang, L.; Celf1 preferentially binds to exon-intron boundary and regulates alternative splicing in hela cells. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2017, 1860(9).