简介
博士毕业于武汉大学，于中山大学肿瘤防治中心进行博士后训练，合作导师为马骏院士，后转聘为中山大学副研究员，硕士生导师，现于马骏院士课题组继续从事基础研究工作，主要研究方向为“鼻咽癌远处转移和治疗抵抗机制”，从表观遗传修饰和泛素化修饰两个角度进行了系列探究，发表SCI论文20余篇，包括Adv Sci（3篇），Nat Commun（3篇），Cell Reports，Cancer Commun，Nat Cancer，JAMA Oncol，Clin Cancer Res 等；主持国自然面上项目2项、青年基金，中国博士后基金，中山大学青年教师培育项目，肿瘤防治中心青年人才提升项目等基金。
发表论文/著作
(1) N6-Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation. Yin Zhao(#); Shengyan Huang(#); Xirong Tan; Liufen Long; Qingmei He; Xiaoyu Liang; Jiewen Bai; Qingjie Li; Jiayi Lin; Yingqin Li; Na Liu; Jun Ma*; Yupei Chen*; Advanced Science, 2022, 9(36): e2205091.（IF 14.3，共一第一）
(2) ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3. Yin Zhao(#); Xiao-Hong Hong(#); Kang Li(#); Ying-Qing Li(#); Ying-Qin Li; Shi-Wei He; Pan-Pan Zhang; Jun-Yan Li; Qian Li; Ye-Lin Liang; Yang Chen; Jun Ma; Na Liu; Yu-Pei Chen*; Cancer Commun, 2020, 40(12): 721-737. （IF 20.1，共一第一，封面论文）
(3) DCAF7 acts as a scaffold to recruit USP10 for G3BP1 deubiquitylation and facilitates chemoresistance and metastasis in nasopharyngeal carcinoma. Qing-Jie Li(#), Xue-Liang Fang(#), Ying-Qin Li(#), Jia-Yi Lin(#), Cheng-Long Huang, Shi-Wei He, Sheng-Yan Huang, Jun-Yan Li, Sha Gong, Kai-Lin Chen, Na Liu; Jun Ma, Yin Zhao*, Ling-Long Tang*. Advanced Science. 2024, 2403262.（IF 14.3，共同通讯，封面论文）
(4) TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models. Jun-Yan Li(#); Yin Zhao(#); Sha Gong(#); Miao-Miao Wang(#); Xu Liu(#); Qing-Mei He; Ying-Qin Li; Sheng-Yan Huang; Han Qiao; Xi-Rong Tan; Ming-Liang Ye; Xun-Hua Zhu; Shi-Wei He; Qian Li; Ye-Lin Liang; Kai-Lin Chen; Sai-Wei Huang; Qing-Jie Li; Jun Ma*; Na Liu*; Nature Communications, 2023, 14(1): 865.（IF 14.7，共一第二）
(5) USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma. Yang Chen(#); Yin Zhao(#); Xiaojing Yang(#); Xianyue Ren(#); Shengyan Huang; Sha Gong; Xirong Tan; Junyan Li; Shiwei He; Yingqin Li; Xiaohong Hong; Qian Li; Cong Ding; Xueliang Fang; Jun Ma; Na Liu*; Nature communications, 2022, 13(1): 501.（IF 14.7，共一第二）
(6) Transcription factor ATMIN facilitates chemoresistance in nasopharyngeal carcinoma. Xue-Liang Fang(#), Qing-Jie Li(#), Jia-Yi Lin(#), Cheng-Long Huang, Sheng-Yan Huang, Xi-Rong Tan, Shi-Wei He, Xun-Hua Zhu, Jun-Yan SLi, Sha Gong, Han Qiao, Ying-Qin Li; Na Liu; Jun Ma, Yin Zhao*, Ling-Long Tang*. Cell Death & Disease 15, 112, 2024.（IF 8.1，共同通讯）
(7) PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma. Sheng-yan Huang(#), Sha Gong(#), Yin Zhao(#), Ming-Liang Ye(#), Jun-Yan Li, Qing-Mei He, Qiao Han, Xi-Rong Tan, Jing-Yun Wang, Ye-Lin Liang, Sai-Wei Huang, Shi-Wei He, Ying-Qin Li, Sha Xu, Ying-Qing Li*, Na Liu*. Nature Communications 15(1): 5300, 2024. （IF 14.7，共一第三）
(8) Chemotherapy-Induced Senescence Reprogramming Promotes Nasopharyngeal Carcinoma Metastasis by circRNA-Mediated PKR Activation. Qian Li(#); Yuheng Zhao(#); Cheng Xu(#); Yelin Liang(#); Yin Zhao(#); Qingmei He; Jun-Yan Li; Kai-Lin Chen, Han Qiao; Na Liu; Jun Ma*; Lei Chen*; Yingqin Li*. Advanced Science, 2023 Jan, 10: e2205668. （IF 14.3，共一第五）
(9) USP2a Supports Metastasis by Tuning TGF-beta Signaling. Yin Zhao; Xiaomeng Wang; Qingqing Wang; Yu Deng; Kang Li; Man Zhang; Qiang Zhang; Jin Zhou; Hong-Yan Wang; Peng Bai; Yujie Ren; Ni Zhang; Weina Li; Yongbo Cheng; Wuhan Xiao; Hai-Ning Du; Xiaoliang Cheng; Lei Yin; Xiangning Fu; Dandan Lin; Qianghui Zhou; Bo Zhong*; Cell Reports, 2018, 22(9): 2442-2454.（独立第一）
(10) WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma. Yin Zhao(#); Wen-Fei Li(#); Qing-Jie Li(#); Shi-Wei He; Qing-Mei He; Liu-Fen Long; Na Liu; Jun Ma*; Oral Oncology, 2021, 122: 105576.（共一第一）
(11) Gemcitabine synergizes with cisplatin to inhibit nasopharyngeal carcinoma cell proliferation and tumor growth. Shi-wei He(#); Yuan Zhang(#); Lei Chen(#); Weijie Luo; Xiao-Min Li; Yang Chen; Sheng-Yan Huang; Qing-Mei He; Xiao-Jing Yang; Ying-Qin Li; Na Liu; Yin Zhao*; Jun Ma*. FASEB journal. 2021 Oct, 35: e21885.（共同通讯）
(12) The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer. Xiaomeng Wang; Ci Yang; Yin Zhao; Zhigao Xu; Wei Yang; Peng Wang; Dandan Lin; Bin Xiong; Jingyuan Fang; Chen Dong; Bo Zhong*. Nature Cancer, 2020 Aug,1:811-825.
(13) Association of Intratumoral Microbiota With Prognosis in Patients With Nasopharyngeal Carcinoma From 2 Hospitals in China. Han Qiao#; Xirong Tan#; Hui Li#; Junyan Li#; Xiao-Zhong Chen; Ying-Qin Li; Wen-Fei Li; Ling-Long Tang; Guan-Qun Zhou; Yuan Zhang; Ye-Lin Liang; Qing-Mei He; Yin Zhao; Shengyan Huang; Sha Gong; Qian Li; Mingliang Ye; Kai-Lin Chen; Ying Sun; Jun Ma; Na Liu*. JAMA Oncology, 2022. 8:1301-1309.
(14) CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization. Xiaohong Hong#; Qian Li#; Junyan Li#; Kailin Chen#; Qingmei He; Yuheng Zhao; Yelin Liang; Yin Zhao; Han Qiao; Na Liu; Jun Ma*; Yingqin Li*. Clinical Cancer Research, 2022.28:4521-35.
